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Culture-Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids.
Edgar RD, Perrone F, Foster AR, Payne F, Lewis S, Nayak KM, Kraiczy J, Cenier A, Torrente F, Salvestrini C, Heuschkel R, Hensel KO, Harris R, Jones DL, Zerbino DR, Zilbauer M. Edgar RD, et al. Among authors: nayak km. Cell Mol Gastroenterol Hepatol. 2022;14(6):1295-1310. doi: 10.1016/j.jcmgh.2022.08.008. Epub 2022 Aug 28. Cell Mol Gastroenterol Hepatol. 2022. PMID: 36038072 Free PMC article.
DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development.
Kraiczy J, Nayak KM, Howell KJ, Ross A, Forbester J, Salvestrini C, Mustata R, Perkins S, Andersson-Rolf A, Leenen E, Liebert A, Vallier L, Rosenstiel PC, Stegle O, Dougan G, Heuschkel R, Koo BK, Zilbauer M. Kraiczy J, et al. Among authors: nayak km. Gut. 2019 Jan;68(1):49-61. doi: 10.1136/gutjnl-2017-314817. Epub 2017 Nov 15. Gut. 2019. PMID: 29141958 Free PMC article.
DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.
Howell KJ, Kraiczy J, Nayak KM, Gasparetto M, Ross A, Lee C, Mak TN, Koo BK, Kumar N, Lawley T, Sinha A, Rosenstiel P, Heuschkel R, Stegle O, Zilbauer M. Howell KJ, et al. Among authors: nayak km. Gastroenterology. 2018 Feb;154(3):585-598. doi: 10.1053/j.gastro.2017.10.007. Epub 2017 Oct 12. Gastroenterology. 2018. PMID: 29031501 Free PMC article.